Restez alertes : on vous dit tout sur la caféine

Stay alert: we tell you everything about caffeine

Coffee is one of the most consumed drinks in the world after water . We have heard too often “don’t drink too much coffee, it’s bad for your health!” ". It's wrong. Coffee consumption is generally safe within usual consumption limits. Quite the contrary, coffee is more likely to improve health than to harm it at doses of 3 or 4 cups of coffee per day. It owes its incredible benefits to caffeine , a molecule whose name we all know and its effective stimulating effect . But do we really know everything?

1. What is caffeine?

Caffeine is a chemical compound found naturally in the seeds, leaves and fruits of different plants . It is a single molecule and, however, depending on its origin, it has several names: caffeine , guarananin , mateine , theine ; respectively depending on whether it is extracted from coffee , guarana , mate or tea . It is also found in other plants, such as the kola nut and in various soft drinks of the same name. The majority of caffeine consumed comes from coffee.

Although discovered and identified as a component of coffee in 1819 by the German chemist Friedlieb Ferdinand Runge, it had actually been consumed since prehistoric times . Legend has it that a goat herder named Kaldi noticed that his goats changed their attitude after grazing on the coffee tree: they seemed euphoric and stayed awake all night. Kaldi therefore tried to consume coffee and felt the same vitality . It was then customary to chew the seeds of this plant to feel its virtues on fatigue, alertness and mood .

2. The benefits of caffeine

The main effects of coffee are due to its action on the nervous system and are demonstrated in numerous clinical studies.


The energizing effect is the best-known benefit of caffeine and is attributed to its role as an adenosine antagonist . To put it simply, when too much energy has been used by the body, it sends a warning signal by secreting adenosine molecules. These adenosine molecules attach to their receptors in the brain, sending a message to the brain to “stop using energy and rest to replenish reserves.” The consequence being falling asleep. But, in the presence of caffeine , it binds to adenosine receptors and sends the opposite message “you must continue to produce and use energy and stay awake ”. The consequence being a state of alert and staying awake noted in several studies (Haskell CF, 2008; Owen GN, 2008; Giesbrecht T, 2020; Cesareo KR, 2019).


In a study published in 2016, carried out on 20 men and 20 women aged 20 to 55 who were administered 200mL of coffee containing 160 mg of caffeine, anti-stress effects were noted via an action on the sympathetic nervous system. ( Papakonstantinou E, 2016).


Caffeine ingested at low doses (65 mg) led to an improvement in memory and reaction time and more generally cognitive performance in a study conducted in 2013 on 128 participants ( Smith AP, 2013; Bruce SE, 2014 ) . This effect on reaction time was also highlighted in a study published in 2008 (Haskell CF, 2008) with 150 mg of caffeine. This study also showed that caffeine reduced mental fatigue. These virtues were also observed in 2010 ( Giesbrecht T, 2010) in 44 young adults in whom alertness was increased and fatigue reduced after ingestion of caffeine coupled with theanine. Finally, caffeine helps support attention and stay focused ( Adan A, 2010; Giesbrecht T, 2010; Bruce SE, 2014; Repantis D, 2021 )


There are countless studies showing the beneficial effects of caffeine on sports performance: improvement in endurance ( Hodgson AB, 2013; Skinner TL, 2019), resistance (Richardson DL, 2016; Romera-Moraleda B, 2019), precision of movements (Zaragoza J, 2019), power and neuromuscular efficiency (San Juan AF, 2019; Jodra P, 2020) , focus , energy and motivation (Cesareo KR, 2019), tension , vigor and vitality (Jodra P, 2020) , muscle strength (Nicks CR, 2020) , recovery ( Mesquita RNO, 2020) and reduction of muscle damage (soreness ) ( Chen HY, 2019).

3. Caffeine in Work & Play

At Reborn, we wanted to develop the most effective product possible to provide energy and improve sports and cognitive performance before training, before an exam or before an evening. So we created our Work & Play product.

The latter could not do without this fabulous active ingredient that is caffeine , which responds to all these problems almost instantly . This caffeine is encapsulated, on the one hand for optimal assimilation and on the other hand to “hide” its bitter taste, in order to offer you the best possible experience in terms of taste and effectiveness .

We have wisely combined caffeine with theanine , because these 2 active ingredients act in synergy to reinforce the positive effects and reduce the negative effects of each. From our knowledge of active ingredients, we know that caffeine can decrease iron absorption , which is why we added iron to our product to compensate for the loss . The vitamin C contained in the product also helps improve iron absorption for perfect bioavailability.

So, it is not enough just to choose the right active ingredients, you also have to combine them well to feel all the benefits and that is Reborn's expertise.

Many of us consume it regularly through our daily coffee, knowing that the extraordinary power of caffeine extends well beyond its energizing properties. Fabulous anti-stress, improver of memory, reaction time, alertness and attention but also booster of sports performance, caffeine never ceases to surprise us. The latest studies even suggest that caffeine could prevent many diseases, particularly neurodegenerative ones (such as Alzheimer's disease).


Let yourself be surprised by the effectiveness of our Work & Play gummies with their delicious wild berry flavor -->

Studies :

  1. Haskell CF , Kennedy DO, Milne AL, Wesnes KA, Scholey AB. The effects of L-theanine, caffeine and their combination on cognition and mood. Biol Psychol. 2008 Feb;77(2):113-22. doi: 10.1016/j.biopsycho.2007.09.008. Epub 2007 Sep 26. PMID: 18006208.
  2. Owen GN , Parnell H, De Bruin EA, Rycroft JA. The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutr Neurosci. 2008 Aug;11(4):193-8. doi:10.1179/147683008X301513. PMID: 18681988.
  3. Adan A, Serra-Grabulosa JM. Effects of caffeine and glucose, alone and combined, on cognitive performance. Hum Psychopharmacol. 2010 Jun-Jul;25(4):310-7. doi:10.1002/hup.1115. PMID: 20521321.
  4. Giesbrecht T , Rycroft JA, Rowson MJ, De Bruin EA. The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness. Nutr Neurosci. 2010 Dec;13(6):283-90. doi:10.1179/147683010X12611460764840. PMID: 21040626.
  5. Hodgson AB , Randell RK, Jeukendrup AE. The metabolic and performance effects of caffeine compared to coffee during endurance exercise. PLoS One. 2013 ;8(4):e59561. doi:10.1371/journal.pone.0059561. Epub 2013 Apr 3. PMID: 23573201; PMCID: PMC3616086.
  6. Smith AP . Caffeine, extraversion and working memory. J Psychopharmacol. 2013 Jan;27(1):71-6. doi:10.1177/0269881112460111. Epub 2012 Sep 26. PMID: 23015541.
  7. Bruce SE , Werner KB, Preston BF, Baker LM. Improvements in concentration, working memory and sustained attention following consumption of a natural citicoline-caffeine beverage. Int J Food Sci Nutr. 2014 Dec;65(8):1003-7. doi:10.3109/09637486.2014.940286. Epub 2014 Jul 21. PMID: 25046515; PMCID: PMC4517431.
  8. Papakonstantinou E , Kechribari I, Sotirakoglou Κ, Tarantilis P, Gourdomichali T, Michas G, Kravvariti V, Voumvourakis K, Zampelas A. Acute effects of coffee consumption on self-reported gastrointestinal symptoms, blood pressure and stress indices in healthy individuals. Nutr J. 2016 Mar 15;15:26. doi:10.1186/s12937-016-0146-0. PMID: 26979712; PMCID: PMC4791892.
  9. Richardson DL , Clarke ND. Effect of Coffee and Caffeine Ingestion on Resistance Exercise Performance. J Strength Cond Res. 2016 Oct;30(10):2892-900. doi: 10.1519/JSC.0000000000001382. PMID: 26890974.
  10. Cesareo KR , Mason JR, Saracino PG, Morrissey MC, Ormsbee MJ. The effects of a caffeine-like supplement, TeaCrine®, on muscular strength, endurance and power performance in resistance-trained men. J Int Soc Sports Nutr. 2019 Oct 28;16(1):47. doi:10.1186/s12970-019-0316-5. PMID: 31660991; PMCID: PMC6816173.
  11. Chen HY, Chen YC, Tung K, Chao HH, Wang HS. Effects of caffeine and sex on muscle performance and delayed-onset muscle soreness after exercise-induced muscle damage: a double-blind randomized trial. J Appl Physiol (1985). 2019 Sep 1;127(3):798-805. doi: 10.1152/japplphysiol.01108.2018. Epub 2019 Jun 20. PMID: 31219772.
  12. Romero-Moraleda B , Del Coso J, Gutiérrez-Hellín J, Lara B. The Effect of Caffeine on the Velocity of Half-Squat Exercise During the Menstrual Cycle: A Randomized Controlled Trial. Nutrients. 2019 Nov 4;11(11):2662. doi:10.3390/nu11112662. PMID: 31690049; PMCID: PMC6893702.
  13. San Juan AF , López-Samanes Á, Jodra P, Valenzuela PL, Rueda J, Veiga-Herreros P, Pérez-López A, Domínguez R. Caffeine Supplementation Improves Anaerobic Performance and Neuromuscular Efficiency and Fatigue in Olympic-Level Boxers. Nutrients. 2019 Sep 5;11(9):2120. doi:10.3390/nu11092120. PMID: 31492050; PMCID: PMC6769736.
  14. Skinner TL , Desbrow B, Arapova J, Schaumberg MA, Osborne J, Grant GD, Anoopkumar-Dukie S, Leveritt MD. Women Experience the Same Ergogenic Response to Caffeine as Men. Med Sci Sports Exercise 2019 Jun;51(6):1195-1202. doi: 10.1249/MSS.0000000000001885. PMID: 30629046.
  15. Zaragoza J , Tinsley G, Urbina S, Villa K, Santos E, Juaneza A, Tinnin M, Davidson C, Mitmesser S, Zhang Z, Taylor L. Effects of acute caffeine, theanine and tyrosine supplementation on mental and physical performance in athletes. J Int Soc Sports Nutr. 2019 Nov 26;16(1):56. doi:10.1186/s12970-019-0326-3. PMID: 31771598; PMCID: PMC6880365.
  16. Jodra P , Lago-Rodríguez A, Sánchez-Oliver AJ, López-Samanes A, Pérez-López A, Veiga-Herreros P, San Juan AF, Domínguez R. Effects of caffeine supplementation on physical performance and mood dimensions in elite and trained- recreational athletes. J Int Soc Sports Nutr. 2020 Jan 3;17(1):2. doi:10.1186/s12970-019-0332-5. PMID: 31900166; PMCID: PMC6942320.
  17. Mesquita RNO, Cronin NJ, Kyröläinen H, Hintikka J, Avela J. Effects of caffeine on neuromuscular function in a non-fatigued state and during tiring exercise. Exp Physiol. 2020 Apr;105(4):690-706. doi:10.1113/EP088265. Epub 2020 Mar 13. PMID: 32092208.
  18. Nicks CR, Martin EH. Effects of caffeine on inspiratory muscle function. Eur J Sport Sci. 2020 Jul;20(6):813-818. doi:10.1080/17461391.2019.1675767. Epub 2019 Oct 17. PMID: 31578132.





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